Lta

Predicted to enable cytokine activity. Acts upstream of or within several processes, including lymph node development; positive regulation of immune response; and positive regulation of type II interferon production. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including extraembryonic component; gut; hemolymphoid system; liver; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha). [provided by Alliance of Genome Resources, Nov 2024]

预测该基因能够激活细胞因子活性。位于多个过程的上游或其中，包括淋巴结发育；免疫反应的正向调节；以及II型干扰素生产的正向调节。预测该基因定位于质膜。预测其在细胞外空间中活性。在多个结构中表达，包括胚外成分；肠道；血淋巴系统；肝脏；以及生殖系统。该基因的人类同源基因与多种疾病有关，包括动脉疾病（多种）；自身免疫疾病（多种）；葡萄糖代谢疾病（多种）；利什曼病（多种）；以及肺部疾病（多种）。与人类LTA（淋巴毒素α）同源。由基因组资源联盟提供，2024年11月。