How olfaction and dietary macronutrient content modulate feeding behaviour in flies and mice

Animals must ingest adequate amounts of nutrients to gain energy for growth and activity. This thesis investigates the role of sense of smell on the way that animals regulate their nutrient intake, using fruit flies and mice. It reveals that poor sense of smell and ageing impair the ability to appropriately regulate nutrient intake. This highlights the role of sense of smell in regulating food intake in a world where it is increasingly common to encounter foods diluted in their nutritional content.