Single cell RNA sequencing mapping the adult human esophagus in vivo and in vitro. Single cell RNA sequencing mapping the adult human esophagus in vivo and in vitro

Despite advances and innovations in characterization of adult esophageal epithelial stem cells, there is still a gap in reliable in vitro methods that closely recapitulate human cell behavior in a physiological-in vivo relevant fashion. Therefore, in this data set we set up to bench mark a detailed single-cell atlas of adult human esophagus with matched in vitro model for long term culture.