five

IL-33 stimulates DCs to express SEMA4A

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE150110
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We hypothesized that IL-33 created Tc1-like condition in the modifying tumor microenvironment (TME). RNA-seq analysis of dendritic cells (DCs) showed the elevation of Il1rl1 and SEMA4A by IL-33, the latter of which was confirmed by qPCR, without significant upregulation of IL-12. We conducted RNA sequencing on IL-33 and PBS treated CD11c+ dendritic cells in triplicate.
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2021-08-15
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