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ChIP-seq analysis of oligodendrocytes treated with demyelinating compound lysolecithin

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP077916
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We performed a series of ChIP-Seq analysis, and demonstrated that Olig2 and its downstream target Gpr17 were the key factors functioning in demyelination process. During demyelination, Olig2 was significantly up-regulated, and Gpr17 was the top ranking Olig2 transcriptional target. Overall design: ChIP-Seq analysis to examine the H3K27Ac and Olig2 recruitment to genome in oligdendrocytes
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2017-09-17
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