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The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2

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Protein Data Bank Japan2025-07-09 更新2026-05-23 收录
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The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2 Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... Authors: Thomsen, M, Neudegger, T, Thieulin-Pardo, G, Blaesse, M, Costanzi, E, Steinbacher, S, Plotnikov, N.V, Dominguez, C, Iyer, R.R, Wilkinson, H.A, Monteagudo, E, Haque, T.S, Prasad, B.C, Finley, M, Boudet, J, Vogt, T.F, Felsenfeld, D.P. Deposit date: 2023-12-01 Release date: 2025-06-11 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (2.526 Å) Cite: The crystal structure of DNA-bound human MutSbeta (MSH2/MSH3) in the canonical mismatch bound conformation with ADP bound in MSH2 and MSH3 To Be Published

结合DNA的人类MutSβ(MSH2_E749A/MSH3_E976A)在经典错配结合构象下的晶体结构,其中腺苷二磷酸(ADP)结合于MSH2亚基 配体描述:1,2-乙二醇、腺苷-5'-二磷酸、氯离子…… 作者:Thomsen M、Neudegger T、Thieulin-Pardo G、Blaesse M、Costanzi E、Steinbacher S、Plotnikov N.V.、Dominguez C、Iyer R.R.、Wilkinson H.A.、Monteagudo E、Haque T.S.、Prasad B.C.、Finley M、Boudet J、Vogt T.F.、Felsenfeld D.P. 提交日期:2023-12-01 发布日期:2025-06-11 最后更新日期:2025-07-09 实验方法:X射线衍射(2.526 Å) 引用文献:结合DNA的人类MutSβ(MSH2/MSH3)在经典错配结合构象且ADP结合于MSH2与MSH3亚基的晶体结构【待发表】

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2023-12-01
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