Synthesis of Naphthalene Amino Esters by the Blaise Reaction of o‑Alkynylarenenitriles
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https://figshare.com/articles/dataset/Synthesis_of_Naphthalene_Amino_Esters_by_the_Blaise_Reaction_of_i_o_i_Alkynylarenenitriles/2308969
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The action of a Reformatsky reagent on o-alkynylarenenitriles provides a convenient access to naphthalene amino esters via tandem 6-endo-dig carbannulation of in situ generated Blaise reaction intermediates. The products are formed in moderate to good yields with high chemo- and regioselectivity.
创建时间：
2016-02-17
