An integrated ABM (Agent-based model)-SIR framework is developed for simulating the spread of an influenza-like pandemic. The SIR model, in this framework, defines three agent states: Susceptible, Inf
The WHO’s early-release guideline for antiretroviral treatment (ART) of HIV infection based on a recent trial conducted in 34 countries recommends starting treatment immediately upon an HIV diagnosis.
BackgroundThe core-group theory of sexually transmitted infections suggests that targeting prevention to high-risk groups (HRG) could be very effective. We aimed to quantify the contribution of hetero
We combine modelling and in vitro measurement of T-cell properties at the level of individual cells. Two types of heterogeneity are explicitly simulated: cell-surface marker expression that is time-de