INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1346370629

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1346370629 Descriptor: (3S,4R)-3-methyl-1-(methylsulfonyl)piperidin-4-amine, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA分析组提交的数据集——SHIP1磷酸酶结构域与C2结构域结合配体Z1346370629的晶体结构。配体描述：(3S,4R)-3-甲基-1-(甲磺酰基)哌啶-4-胺、二甲基亚砜、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1。作者：Bradshaw W.J.、Newman J.A.、von Delft F.、Arrowsmith C.H.、Edwards A.M.、Bountra C.、Gileadi O. 提交日期：2020-10-30；发布日期：2020-11-11；最后修改日期：2026-02-18。实验方法：X射线衍射（分辨率1.55 Å）。引用文献：《通过SHIP1与SHIP2的C2结构域调控肌醇5-磷酸酶活性》，《Structure》，2024年。