Relative risk for severe hypoglycemia and hypoglycemic coma per year from 1995 to 2012 by HbA1c category.

Results calculated from regression models with severe hypoglycemia or hypoglycemic coma as the dependent variable, adjusted for treatment year (continuous term), HbA1c category, sex, age, and diabetes duration, and with a term for interaction between HbA1c and treatment year. RRs with 95% CIs. p-Values from Wald tests are related to RR. Conversion for HbA1c [mmol/mol] = (HbA1c [percent] − 2.15) ×10.929.*Additionally adjusted for insulin treatment regimen (1–3 or ≥4 insulin injection time points per day, or insulin pump therapy).Relative risk for severe hypoglycemia and hypoglycemic coma per year from 1995 to 2012 by HbA1c category.