Structure of the D125N mutant of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor

Structure of the D125N mutant of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor Descriptor: (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, 1,2-ETHANEDIOL, Alpha-1,6-mannanase, ... Authors: Davies, G.J, Offen, W.A. Deposit date: 2020-06-09 Release date: 2021-04-28 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27, 2021

环状芽孢杆菌（Bacillus circulans）α-1,6-甘露聚糖酶（Alpha-1,6-mannanase）催化结构域D125N突变体与α-1,6-α-甘露糖-环菲糖醇（cyclophellitol）三糖抑制剂的复合物结构。描述符：(1S,4S,5R)-6-(羟甲基)环己烷-1,2,3,4,5-五醇、1,2-乙二醇、α-1,6-甘露聚糖酶…… 作者：Davies, G.J.、Offen, W.A. 存入日期：2020-06-09 发布日期：2021-04-28 最后修改日期：2024-10-23 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.4埃（Å）。引用文献：《基于不可水解寡糖的内切聚糖酶活性灭活剂开发：以α-1,6-甘露聚糖酶为例》，《Chemistry》，2021年，第27卷。