Antitumoral activity of acadesine and rituximab in MCL
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE47871
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资源简介：
Acadesine is a nucleoside analogue with known antileukemic effects in different neoplasms. We investigated the activity of acadesine ne exerts a cytotoxic effect in MCL and synergizes with rituximab supporting clinical examination of this strategy for MCL patients We used microarrays to detail the gene expression changes in acadesine-, rituximab- and combination-treated tumors. Global RNA expression in tumors treated with acadesine, rituximab and the combination in a xenograft model of MCL (Jeko-1). Tumors were collected 18 days after the initiation of the treatments.
创建时间：
2019-03-21
