Gene expression analysis in liver of rats fed with atherogenic diet (1% cholesterol) and supplemented with 5% Geneva or 5% Hayward kiwifruit lyophylisate. Rattus norvegicus

Transcriptional profiling of liver tissue from rats fed with standard diet with 1% cholesterol (control diet) and the same diet supplemented with 5% Geneva (test sample1) or 5% Hayward (test sample2) kiwifruit lyophylisate. The goal was to determine the anti-atherogenic effect of kiwi fruit supplementation and their impact on gene expression preventing hepatic steatosis Overall design: Three-condition experiment. (1) Liver samples from rats fed with standard diet with 1% cholesterol (control diet) vs. the same diet supplemented with (2) 5% Geneva (test sample1) or (3) 5% Hayward (test sample2) kiwifruit lyophylisate. Biological replicates: 8 control replicates (1), 8 reps of examined condition1 (2) , 8 reps of examined condition2 (3)