FLANC, a novel primate-specific long non-coding RNA, is involved in colorectal carcinogenesis and holds potential as a novel therapeutic target (shRNA)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE127785
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FLANC is significantly up-regulated in two cohorts of CRC samples and high level of FLANC is associated with poor patient survival in two additional independent cohorts. FLANC influences cellular growth, apoptosis, migration and metastases formation of CRC cells. We performed genome-wide microarray expression profiling to study the genetic landscape alterations induced by the knock-down of FLANC by shRNA in HCT-116 cells.
创建时间:
2020-03-27



