Additional file 7: Table S1. of System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia
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Table for the combinatorial numerical tests. Qualitative results of the numerical tests on combinations of possible regulatory relations are documented here, with all 81 combinations exhausted. The first four columns represent the regulatory code, “1” – inhibitory, “2” – none, and “3” – activatory effects, respectively. Molecular actions are indicated by the column headers. The last two columns show the agreement or discrepancy with input experimental data, “0” qualitative discrepancy, “1” qualitative agreement. The input experimental data for model training are the cell-cycle status after transduction of Maff/Egr3 and qRT-PCR results for cell-cycle genes. (XLSX 13 kb)
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2017-10-04



