Effects of model chylomicron remants on gene expresssion in human aortic endothelial cells (HAEC). Homo sapiens

Global gene experssion study of the HAEC transcriptional response to artificial chlyomicron remnant-like particles (A-CRLPs) prepared with triglycerides extracted from four natural dietary oils: fish, DHASCO, corn and palm oils. We hypothesised that A-CRLPs could differentially regulate HAEC gene expression according to thier triglyceride content. These data provide an important starting point for investigations into the effects of A-CRLPs on endothelial cells, particulary genes involved in redox balance and inflammatory processes. Overall design: Six experimental conditions: PBS (extra control), Primary/main control remnant control (RC), Fish, DHASCO, Corn or Palm A-CRLPs n = 4 biological replicates (i.e. 4 HAEC batches from different donors)