Transcriptional heterogeneity of HCC1143 Triple Negative Breast Cancer perturbed with paclitaxel or soluble ligand. Transcriptional heterogeneity of HCC1143 Triple Negative Breast Cancer perturbed with paclitaxel or soluble ligand

Triple Negative Breast cancer is a heterogeneous disease that is capable of adapting to a variety of stimuli. To study the dynamics of both drug and ligand response, we performed scRNA-seq to deeply profiled the transcriptional response of the HCC1143 cell line to a variety of stimuli. Overall design: HCC1143 cells were grown in vitro and treated for 24 or 72 hours with soluble perturbation.