Effect of Combination Therapy on Drug Potency.
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Morphine and clonidine were administered in a dose-ratio of 1∶1 for spinal and 10∶1 for systemic administration; ∼ indicates that the ED50 value was determined by extrapolation (in cases where maximum efficacy was between 30 and 50%); γ = Interaction index (an index of 1 = no interaction, index >1 = potentiation, index <1 = antagonism); * indicates that the ED50 value of clonidine alone was not significantly different from that of clonidine in the presence of morphine; NA = not available (it is not possible to calculate these values).
Effect of Combination Therapy on Drug Potency.
创建时间:
2014-10-09



