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Bulk ATAC sequencing in HUVEC after ZBTB16-repression

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP603255
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ZBTB16 is a transcription factor that is known to induce or repress gene expression. RNA sequencing data from ZBTB16-silenced mice showed that ZBTB16-deletion induces an aged-like phenotype in endothelial cells. In order to understand how ZBTB16 alters gene expression in endothelial cells, ATAC-seq was performed on HUVEC after siTNA-mediated ZBTB16-silencing. Overall design: HUVEC were transfected with siRNA pools targeting ZBTB16 or with non-targeting siRNAs. Three days after transfection, cells were lysed.
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2026-01-09
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