Levonorgestrel intrauterine device versus combined transcervical resection of the endometrium and levonorgestrel intrauterine device in the management of Adenomyosis: A randomized clinical trial.

Adenomyosis is an important cause of abnormal uterine bleeding and dysmenorrhea in reproductive aged women. Levonorgestrel intrauterine device (LNG-IUD) is one of the commonly used treatment option in women with Adenomyosis. However, LNG-IUD has a relatively high failure rate in Adenomyosis. Combining Transcervical resection of endometrium (TCRE) with LNG-IUD may reduce the failure rate of LNG-IUD in women with Adenomyosis. This RCT was done to compare the efficacy of combined TCRE and LNG-IUD versus LNG-IUD alone in women with Adenomyosis.子宫腺肌症（Adenomyosis）是育龄女性异常子宫出血与痛经的重要病因。左炔诺孕酮宫内节育器（Levonorgestrel intrauterine device, LNG-IUD）是子宫腺肌症患者常用的治疗手段之一。然而，左炔诺孕酮宫内节育器用于子宫腺肌症治疗时失败率相对偏高。将经宫颈子宫内膜切除术（Transcervical resection of endometrium, TCRE）与左炔诺孕酮宫内节育器联合应用，可降低子宫腺肌症患者使用该节育器的失败率。本随机对照试验（Randomized Controlled Trial, RCT）旨在对比经宫颈子宫内膜切除术联合左炔诺孕酮宫内节育器与单纯使用左炔诺孕酮宫内节育器治疗子宫腺肌症的临床疗效。