iPS derived melanocyte precursor cells

We found distinct and self-renewal cell linages that could differentiate into melanocytes, named melanocyte precursor cells (MPCs) in which MPCs revealed drastically differntiation to authentic melanocytes by a small amount of GSK3β inhibitor in about seven days. Comparing MPCs ,iPSCs and melanocytes, we showed wnt sigal systems in differentiation to melanocytes. We extracted total RNA from iPSCs, MPCs,induced melanocytes from iPSCs and human epidermal melanocytes and hybridized them to Agilent gene expression microarrays.