Supplemental Content EBM review of literature - CHM report isotretinoin

This is a supplementary document with detailed information on the review of the literature cited by the Commission on Human Medicine (CHM) working group on Isotretinoin. Supplementary eTable 1 includes references cited by the CHM and graded according to Oxford EBM level, study type and patient numbers. Supplementary eTable 2 includes the CARM report on isotretinoin and dispensing data from the Pharmaceutical Data Webtool本文件为补充材料，详细记载了人类医学委员会（Commission on Human Medicine, CHM）异维A酸（Isotretinoin）工作组所引用文献的综述相关信息。补充电子附表1收录了该委员会引用的全部文献，并依据牛津循证医学（Evidence-Based Medicine, EBM）等级、研究类型及受试者人数完成分级。补充电子附表2收录了针对异维A酸的CARM报告，以及来自药品数据网络工具的配药数据。