Supplementary materials: An impact evaluation of an education bundle for patients at risk of developing venous thromboembolism

These are peer-reviewed supplementary materials for the article 'An impact evaluation of an education bundle for patients at risk of developing venous thromboembolism' published in the Journal of Comparative Effectiveness Research.Supplementary material: Parameter Values – Table 1: Parameters Used in the Model of Education Bundle for Patients at Risk of Developing VTESupplementary material: List of Modeling Assumptions – Table 2 Aim: Among hospitalized patients, venous thromboembolism (VTE) is a preventable cause of morbidity and mortality. This study analyzed the effects of a large-scale adoption of a prompt response and education protocol to increase VTE prophylaxis adherence in the USA. Methods: A Markov model was developed that simulates outcomes and costs of delivering a VTE education bundle versus not, to hospitalized at-risk patients. Results: The education bundle could avert more than 134,000 VTEs, 552,000 hospital days and 19,000 deaths over 5 years. Patients could save 13 million hours in work absenteeism and travel time, valued at US$237 million. Total societal savings could amount to US$2.8 billion. In scenario analyses with assumed lower-effectiveness estimates, the bundle averts 16,000 VTEs, 67,000 hospital days and 2000 deaths. Conclusion: A nationwide rollout of an education bundle to reduce missed doses of prescribed prophylaxis could improve quality of care, resulting in a decline in VTEs and mortality.

本数据集为发表在《比较效果研究杂志》上的文章《评估预防静脉血栓栓塞症的教育套餐对易感患者的影响》的同行评审补充材料。补充材料：参数值 - 表1：用于预防静脉血栓栓塞症教育套餐模型中的参数；补充材料：建模假设列表 - 表2。研究目的：在住院患者中，静脉血栓栓塞症（VTE）是一种可预防的疾病负担和死亡原因。本研究分析了在美国大规模采用快速响应和教育协议以增加VTE预防措施依从性的影响。研究方法：开发了一个马尔可夫模型，模拟了向住院的易感患者提供与不提供静脉血栓栓塞症教育套餐的结局和成本。研究结果：教育套餐可以在5年内预防超过134,000例VTE、552,000个住院日和19,000例死亡。患者可以节省13百万小时的工作缺勤和旅行时间，其价值约为2.37亿美元。在社会经济情景分析中，假设效果估计较低，该套餐可以预防16,000例VTE、67,000个住院日和2,000例死亡。研究结论：在全国范围内推广教育套餐以减少遗漏预防性药物剂量，有望提高医疗质量，从而降低VTE和死亡率。