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Hedgehog pathway analysis in both CD138+ and B-cells obtained from newly diagnosed Multiple Myeloma patients

ChEBI2016-05-31 更新2026-07-12 收录

多发性骨髓瘤分子机制

Hedgehog信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69000 数据链接链接失效反馈

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Hedgehog pathway analysis in both CD138+ and B-cells obtained from newly diagnosed Multiple Myeloma patients

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创建时间：

2016-05-31

癌症分子机制

Hedgehog信号通路

The Hedgehog pathway is a potent regulator of cellular growth and plays a central role in the development of many cancers including basal cell carcinoma (BCC). The majority of BCCs arise from mutation

NIAID Data Ecosystem60

Gene expression signatures for human interleukin-6 (IL-6) treatment in human multiple myeloma (MM) cell lines.. Gene expression signatures for human interleukin-6 (IL-6) treatment in human multiple myeloma (MM) cell lines.

多发性骨髓瘤分子机制

基因表达谱分析

To investigate the effect of IL-6 on gene expression in IL-6-dependent MM cell lines, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the p

NIAID Data Ecosystem60

MRTF/SRF link the cytoskeleton and hedgehog pathway in drug-resistant basal cell carcinomas

化疗耐药机制

Hedgehog信号通路

We use multi-dimensional genomic analysis using mouse resistant BCCs to identify a non-canonical hedgehog activation pathway driven by the transcription factor, serum response factor (SRF). RNA and wh

NIAID Data Ecosystem50

Gene expression of myeloma patient samples under hypoxia

多发性骨髓瘤分子机制

低氧基因表达

We conducted whole genome gene screening against the MM patients bone marrow (sorted by CD38++) cells that were subjected by chronic hypoxia condition. We compared four primary myeloma samples culture

NIAID Data Ecosystem60

Combined constitutive canonical and non-canonical HH signaling caused by depletion of Patched 2 causes an MPN phenotype and transforms chronic MPNs into acute leukemias

Hedgehog信号通路

骨髓增殖性肿瘤转化机制

Combined constitutive canonical and non-canonical HH signaling caused by depletion of Patched 2 causes an MPN phenotype and transforms chronic MPNs into acute leukemias

ChEBI2016-01-11 更新60

Hedgehog pathway analysis in both CD138+ and B-cells obtained from newly diagnosed Multiple Myeloma patients

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