Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659E Mutation Identified in Endometrial Cancer.
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659E Mutation Identified in Endometrial Cancer. Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION Authors: Chen, H, Mohammadi, M. Deposit date: 2013-02-15 Release date: 2013-08-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5482 Å) Cite: Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations. Cell Rep, 4, 2013
子宫内膜癌中鉴定出的携带致病性功能获得性K659E突变的成纤维细胞生长因子受体2(Fibroblast Growth Factor Receptor 2, FGFR2)激酶结构域晶体结构。描述项:成纤维细胞生长因子受体2、膦酰甲基膦酸腺苷酯、硫酸根离子。作者:Chen H、Mohammadi M。提交日期:2013-02-15。发布日期:2013-08-07。最后修改日期:2023-09-20。实验方法:X射线衍射(2.5482 Å)。引用文献:《通过致病性功能获得性突变分析解析内在酪氨酸激酶活性的分子起源》,《细胞报告》(Cell Rep),第4卷,2013年
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2013-02-15



