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Hydrazone compounds are active under hypoxia.

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Figshare2018-10-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Hydrazone_compounds_are_active_under_hypoxia_/7219061
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M. tuberculosis was cultured in DTA medium in the Wayne model of hypoxia for 18 days to generate the non-replicating state. Bacteria were inoculated into plates containing compounds and incubated for 9 days under hypoxia (anaerobic) or 6 days in air (aerobic). Growth was measured by luminescence. IC90 is the concentration required to inhibit growth by 90%. Results are the mean ± standard deviation from a minimum of two experiments.
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2018-10-17
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