PKCeta kinase domain in complex with compound 11

PKCeta kinase domain in complex with compound 11 Descriptor: (3P)-3-{4-[(3R,5S)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile, Protein kinase C eta type Authors: Johnson, E. Deposit date: 2023-01-03 Release date: 2023-04-05 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1. J.Med.Chem., 66, 2023与化合物11结合的蛋白激酶Cη（PKCeta）激酶结构域，描述物：(3P)-3-{4-[(3R,5S)-3-氨基-5-甲基哌啶-1-基]-6-氯-7H-吡咯并[2,3-d]嘧啶-5-基}苯甲腈，所属蛋白为η型蛋白激酶C。作者：E·约翰逊。提交日期：2023-01-03。发布日期：2023-04-05。最后修改日期：2024-10-09。实验方法：X射线衍射（分辨率2.3埃）。引用文献：《造血祖细胞激酶1的功能性活性5-氨基-6-芳基吡咯并嘧啶抑制剂的设计与合成》，《药物化学杂志》，66卷，2023年。