Quantitative transcriptome analysis of the repair mechanism of AKBA on the treatment of rat sciatic nerve injury

The data obtained through differential mRNA expression analysis showed that 258 genes were significantly differentially expressed at the mRNA level in the AKBA group relative to in the model group . These genes included 189 upregulated genes and 69 downregulated genes. A total of 355 genes, including 194 upregulated genes and 161 downregulated genes, were significantly differentially expressed at the mRNA level in the AKBA group relative to in the sham operation group . A total of 410 genes, among which 171 were upregulated and 239 were downregulated, were significantly differentially expressed at the mRNA level in the sham operation group relative to in the model group. The results showed that significantly differentially expressed genes in the AKBA and model control groups were enriched in 193 pathways. The the highest enrichment the phagosome pathways. Overall design: SD rats with sciatic nerve injury model, model group treated with AKBA, and sham operation group Please note that the data columns in the 'mRNA_Expression_Summary.xlsx" correspond to the samples as following: GYZ = A KBZ = M JSSZ = S