Super-enhancer-associated TTC8 promotes neuroblastoma progression
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP345436
下载链接
链接失效反馈官方服务:
资源简介:
We report a previously unrecognized role of super-enhancer-associated TTC8 in neuroblastoma. To explore TTC8-dependent gene regulation, RNA-seq analysis was conducted and the differently expressed genes were revealed in the TTC8-knockdown SK-N-BE(2) cells in comparison to control group. We find that TTC8 activate the MAPK signaling pathway to promote the occurrence and development of neuroblastoma. Overall design: mRNA profiles of SK-N-BE(2) cells transfected with scramble shRNA (sh-Scb) or sh-TTC8 were generated by RNA sequencing, in double, using Illumina NovaSeq6000.
创建时间:
2022-11-11



