One Hundred Carboxylate Receptors

This
work presents a compilation of binding constant (logKass) values in DMSO-d6/H2O (0.5%
m/m) for a variety of receptors with 12 carboxylate anions
(formate, acetate, lactate, pivalate, sorbate, hexanoate, benzoate,
glyphosate, glucuronate, ibuprofen, naproxen, and ketoprofen). A total
of 489 logKass values are listed for 100
anion receptor molecules. Most logKass values originate from previously published articles, along with
some values for previously unpublished receptor molecules, spanning
a workflow of 8 years. The purpose of this study is to serve as a
comprehensive information source for selecting suitable receptor candidates
to be used in practical carboxylate sensing applications, such as
constructing ion-selective electrodes (ISE-s). To support such decision
making, all receptors are presented together with lipophilicity (logPo/w) data.