Mechanical Strain Drives Myeloid Cell Differentiation Toward Pro-Inflammatory Subpopulations
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE175460
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资源简介：
We quantify the effects of mechanical strain on three-dimensional (3D) cultured mouse myeloid cells at the cellular and transcriptomic level using single cell RNA-sequencing. We demonstrate that mechanical stress induces pro-inflammatory fates. scRNA-seq was performed on mouse myeloid cells from 5 mice in physiologically relevant, 3-dimensional, in vitro, collagen scar systems
创建时间：
2021-07-23
