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Macrophage-produced VEGFC is induced by efferocytosis to resolve inflammation and improve ventricular function after myocardial infarction (RNA-Seq)

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP360145
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资源简介:
Recent reports have suggested a protective role for vascular endothelial growth factor C (VEGFC) during acute cardiac lymphangiogenesis post MI. Glinton et al. report that defective efferocytosis by macrophages after experimental MI leads to a reduction in cardiac lymphangiogenesis and Vegfc expression. Overall design: Bulk mRNA sequencing 9 days post injury of cardiac extracts of Vegfcfl/fl versus Vegfcfl/fl;LysMCre mice subjected to coronary artery occlusion
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2022-07-01
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