Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase
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Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase Descriptor: 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. Deposit date: 2003-05-19 Release date: 2003-12-09 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
人二氢叶酸还原酶(human dihydrofolate reductase)结合5-甲基-6-N-甲基苯胺基嘧啶类抗叶酸剂复合物的三次晶体结构解析分析
描述符:2,4-二氨基-5-甲基-6-[(3,4,5-三甲氧基-N-甲基苯胺基)甲基]吡啶并[2,3-d]嘧啶、二氢叶酸还原酶、还原型烟酰胺腺嘌呤二核苷酸磷酸(NADPH,dihydronicotinamide adenine dinucleotide phosphate)
作者:Cody V、Luft J.R、Pangborn W、Gangjee A
提交日期:2003年5月19日
发布日期:2003年12月9日
最后修改日期:2023年8月16日
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.1埃(Å)
引用文献:人二氢叶酸还原酶结合5-甲基-6-N-甲基苯胺基嘧啶类抗叶酸剂复合物的三次晶体结构解析分析。《晶体学学报D辑》,59卷,2003年
创建时间:
2003-05-19



