Supplementary Material for: Renal-type clear cell carcinoma of the prostate: a rare case report

Occurrence of clear cell carcinoma of the prostate is exceedingly rare and presents a diagnostic dilemma. We describe a case of a 47-year- old male nonsmoker, who presented with a history of frequency dribbling urination and dysuria for six-months. In a digital rectal exam, enlarge prostate with a hard consistency was identified. All results for hematological and biochemical tests were normal. Also serum prostate-specific-antigen (PSA) level was 2.7 ng/ml (within normal range). Open prostatectomy was done and the result showed a 300 gr specimen and histopathology examination revealed clear cell carcinoma. Computerized tomography (CT) scan and ultrasound did not show any mass in kidneys but three nodules in both lungs in favor of metastasis were identified. Three months after surgery PET scan revealed hyperactivity in the abdominal wall, pelvic lymph nodes and lung fields in favor of metastasis thereafter systemic therapy with tyrosine kinase inhibitor was prescribed. To the best of our knowledge, clear cell carcinoma of the prostate has been reported very rarely.