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Additional file 10 of Sex specific molecular networks and key drivers of Alzheimer’s disease

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Additional file 10: Supplemental Table 10. The top network drivers of female AD. Candidate genes of the top AD-associated modules in the gene network of the PHG from the female AD subjects in the MSBB cohort and in the gene network of the PFC from the female AD subjects in the ROSMAP cohort. Genes that met any of three selection criteria were selected and further rank-ordered based on the strength of association with AD. The rank order was calculated based on multiple p values calculated from module-trait correlation and module-DEG enrichment analyses with a candidate score which ranges from 0 to 1. Number of the published literature on each specific candidate gene was also shown.
提供机构:
Wang, Minghui; Goate, Alison; Lee, Yeji; Zhou, Xianxiao; Bu, Guojun; Chao, Michael; Huang, Min; Zhang, Bin; Cao, Jiqing; Cai, Dongming; Liu, Chia-Chen; Guo, Lei; Li, Yonghe; Zhu, Li; Duarte, Mariana Lemos; Martens, Yuka; Hou, Jianwei; Haroutunian, Vahram; Zhang, Larry
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2024-08-13
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