Data Properties and Statistics.
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The nature of the topology is best described by taking measurements of its representative graph (formulated as discussed in the Curation section of the Methods). Curation and SCC removal (by its nature) reduces connectivity within the graph, leading to the observed differences between the curated/uncurated pairs. Reactome, by contrast, is a much larger dataset with much greater complexity, as shown in number of connected components and the characteristic path length.
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2015-12-02



