Global transcriptomics analysis for TDO2 alteration in human triple-negative breast cancer cell lines
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE253237
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资源简介：
To elucidate the downstream transcriptomics changes in reponse to TDO2 alteration including shRNA knockdown, overexpression and TDO2/IDO duak inhibitor treatments in human triple-negative breast cancer cell lines. Each condition with biological triplicates. Human triple-negative breast cancer cell line BT549 with TDO2 overexpression (OE) in compared with control empty vector (EV); BT549 with shRNA TDO2 knockdown (shTDO2-082 or shTDO2-098) vs. shNegative control (shNeg); BT549 at forced suspension culture treated with TDO2/IDO dual inhibitor AT0174 for 48 hours ; SUM159PT at forced suspension culture treated with TDO2/IDO dual inhibitor AT0174 for 48 hours
创建时间：
2025-01-03
