Predictive assessment of BALB specific amino acid polymorphisms for potentially damaging alterations.

We list the polymorphisms using MPD (Mouse Phenome Database) and known functional domains using STRING (Search Tool for the Retrieval of Interacting Genes/Proteins) within the Mrip regions. Polyphen predictions are based on position specific independent count (PSIC) and if >1.5 then potentially damaging and shown in bold. SIFT predicts the substitution to be tolerated (T) or not tolerated (N), if intolerant then the substitution effect is stated. The conservation of sequence alignment at and around the amino acid substitution is compared using EMBL-EBI.