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Rice met1-2 mutant callus multi omics sequencing data

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA557819
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CG methylation (mCG) is essential for preserving genome stability in mammals, but this link remains obscure in plants. OsMET1-2 is the major rice DNA methyltransferase, plays critical roles in maintaining mCG in rice. Null mutation of OsMET1-2 causes massive CG hypomethylation, rendering the mutant suitable to address the role of mCG in maintaining genome integrity in plants. Here, we sequenced the genome, methylome, and transcriptome of tissue cultures of OsMET1-2 homozygous (-/-) and heterozygous (+/-) mutants, and isogenic wild-type, for exploring the role of mCG on rice genome stability and TE mobility.
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2019-08-01
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