Oral iron plus ascorbic acid supplementation and martial status (Sideral; PI: P Perazzo)

Raw data of the clinical trial NCT04078880. We enrolled older adults scheduled for hip/knee surgery and we randomized them to a pre-operative supplementation program with iron and L-ascorbic acid or to the control group. Adjustments for confounding factors, such as iron absorption influencers, showed a relevant response limited to older patients (≥ 65 years old), whose uncharacterized Hb loss was averted upon treatment with iron formula. The dataset was used to write the article "Oral Supplementation with Sucrosomial Ferric Pyrophosphate Plus L-Ascorbic Acid to Ameliorate the Martial Status: A Randomized Controlled Trial", which was published by the Journal Nutrients in 2020.临床试验NCT04078880的原始数据。本研究招募了拟接受髋/膝关节手术的老年受试者，将其随机分配至术前补铁联合L-抗坏血酸（L-ascorbic acid）补充干预组与对照组。对铁吸收影响因素等混杂因素进行校正后发现，干预效应仅局限于≥65岁的老年患者群体：该群体未明确表征的血红蛋白（Hb）丢失可通过补铁制剂干预得到逆转。本数据集用于撰写论文《口服蔗糖焦磷酸铁（Sucrosomial Ferric Pyrophosphate）联合L-抗坏血酸补充干预改善机体功能状态：一项随机对照试验》，该论文于2020年发表于期刊《营养素》（Nutrients）。