DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma
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https://www.ncbi.nlm.nih.gov/sra/SRP113612
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资源简介：
We performed methylation profiling using RRBS-seq to investigate the role of DNMT3B in MYC-driven tumor maintenance. Comparing tumor cells before and upon DNMT3B knock-down revealed genome-wide changes in the DNA methylation pattern. Overall design: Samples used in this study correspond to T-cell acute lymphoblastic leukemia (T-ALL) cell lines derived from EµSRa-tTA;tet-o-MYC mice.
创建时间：
2017-11-07
