ATF3 aggravates kidney fibrosis via HDAC6-dependent epigenetic reprogramming

NIAID Data Ecosystem2026-05-02 收录

纤维化机制

表观遗传调控

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Raw bands of all western blotting results and raw data for RNA-seq analyses.

创建时间：

2025-08-18

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The top 10 active ingredients.

纤维化机制

中药活性成分

A number of studies demonstrate the therapeutic effectiveness of Radix Bupleuri (RB) and Hedysarum Multijugum Maxim (HMM) in treating liver fibrosis, but the exact molecular mechanisms remain unclear.

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Addressing the specific roles of histone modifications in transcriptional repression [RNA-seq]

组蛋白修饰转录抑制

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Our understanding of epigenetic processes is based on the hypothesis that individual posttranslational modifications of DNA and histones, or combinations thereof, function to direct unique downstream

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ATF3 aggravates kidney fibrosis via HDAC6-dependent epigenetic reprogramming

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