SLMB binds to phosphorylated ARM to form the 'destruction complex'

The phosphorylated Armadillo (ARM) is now recognised and bound by the F-box protein Slimb (SLMB), in the E3 ubiquitin ligase assembled complex additionally containing the S-phase kinase-associated protein SKPA, the Cullin orthologue, LIN19, the Ring-box protein containg ROC1A, and the ubiquitin-conjugating enzyme orthologue EFF.

磷酸化的装甲蛋白（ARM）现已被F-box蛋白Slmb（SLMB）识别并结合，该F-box蛋白是组成E3泛素连接酶复合体的一部分，该复合体还包括S期激酶相关蛋白SKPA、Cullin同源蛋白LIN19、含有ROC1A的Ring-box蛋白以及泛素结合酶同源蛋白EFF。