Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein

Protein Data Bank Japan2025-06-04 更新2026-03-28 收录

下载链接：

https://pdbj.org/mine/summary/7try

下载链接

链接失效反馈

官方服务：

资源简介：

Cryo-EM structure of corticotropin releasing factor receptor 2 bound to Urocortin 1 and coupled with heterotrimeric G11 protein Descriptor: Corticotropin-releasing factor receptor 2, G protein gamma subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Zhao, L.-H, Lin, J, Mao, C, Zhou, X.E, Ji, S, Shen, D, Xiao, P, Melcher, K, Zhang, Y, Yu, X, Xu, H.E. Deposit date: 2022-01-31 Release date: 2022-11-09 Last modified: 2025-06-04 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure insights into selective coupling of G protein subtypes by a class B G protein-coupled receptor. Nat Commun, 13, 2022

结合尿皮质素1（Urocortin 1）并与异三聚体G11蛋白偶联的促肾上腺皮质激素释放因子受体2（corticotropin releasing factor receptor 2）的冷冻电镜（Cryo-EM）结构描述符：促肾上腺皮质激素释放因子受体2、G蛋白γ亚基、鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(T)亚基β-1等作者：Zhao, L.-H、Lin, J、Mao, C、Zhou, X.E、Ji, S、Shen, D、Xiao, P、Melcher, K、Zhang, Y、Yu, X、Xu, H.E. 存档日期：2022-01-31 发布日期：2022-11-09 最后修改日期：2025-06-04 实验方法：电子显微镜（分辨率3.7 Å）引用文献：《一类B型G蛋白偶联受体选择性偶联G蛋白亚型的结构机制》，《自然通讯（Nat Commun）》，第13卷，2022年

创建时间：

2022-01-31