Human exosomal placenta-specific miRNAs modulate expression of target genes in maternal immune cells during pregnancy

ChEBI2013-09-13 更新2026-07-21 收录

胎盘外泌体miRNA

妊娠免疫调节

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Human exosomal placenta-specific miRNAs modulate expression of target genes in maternal immune cells during pregnancy

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2013-09-13

B cells acquire a unique and differential transcriptomic profile during pregnancy in mice. B cells acquire a unique and differential transcriptomic profile during pregnancy in mice

妊娠免疫调节

B细胞转录组

Pregnancy significantly alters B cells development and function. B cell activation is initiated by antigens specific binding to the BCR, leading to an intricate signaling pathway responsible for B cel

NIAID Data Ecosystem60

Total uterus transcriptome after depletion of regulatory T cells at E8 of murine pregnancy. Total uterus transcriptome after depletion of regulatory T cells at E8 of murine pregnancy

妊娠免疫调节

转录组分析

Regulatory T cells (Tregs) contribute to successful pregnancy by promoting maternal-fetal tolerance. We depleted Tregs using diphtheria toxin (DT) in the Foxp3DTR mouse model after allogenic mating wi

NIAID Data Ecosystem60

Table_2_Progesterone Dampens Immune Responses in In Vitro Activated CD4+ T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy.xlsx

妊娠免疫调节

自身免疫性疾病基因表达谱

The changes in progesterone (P4) levels during and after pregnancy coincide with the temporary improvement and worsening of several autoimmune diseases like multiple sclerosis (MS) and rheumatoid arth

NIAID Data Ecosystem50

Table_2_Clonally Expanded Decidual Effector Regulatory T Cells Increase in Late Gestation of Normal Pregnancy, but Not in Preeclampsia, in Humans.XLSX

妊娠免疫调节

子痫前期病理机制

Background: Regulatory T (Treg) cells are necessary for the maintenance of allogenic pregnancy. However, the repertoire of effector Treg cells at the feto-maternal interface in human pregnancy remains

NIAID Data Ecosystem60

Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology

胎盘外泌体miRNA

母胎免疫互作

The role of extracellular vesicles (EVs), specifically exosomes, in intercellular communication likely plays a key role in placental orchestration of pregnancy and maternal immune sensing of the fetus

NIAID Data Ecosystem50

Human exosomal placenta-specific miRNAs modulate expression of target genes in maternal immune cells during pregnancy

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