Differential gene expression in neuroblastoma cells after treatment with JQ1, nanaomycin, or combination of JQ1 and nanaomycin
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76066
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资源简介：
BET bromodomain inhibitors are emerging as very promising novel anticancer agents. Combination of BET bromodomain inhibitor JQ1 and quinone-containing compound nanaomycin exerts synergistic anticancer effect in neuroblastoma We analysed whether a treatment with BET bromodomain inhibitor JQ1, and quinone-containing compound Nanaomycin synergistically modulate gene expression Neuroblastoma BE(2)-C cells were treated with vehicle control, 500nM JQ1, 125nM nanaomycin, or combination of JQ1 and nanaomycin. RNA was extracted from the cells 6 hours after treatment, and subjected to differential gene expression studies with Affymetrix microarrays.
创建时间：
2018-07-26
