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Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

NIAID Data Ecosystem2026-05-01 收录

结核病药物靶点

转录调控因子结构

数据链接：

https://www.rcsb.org/structure/7NGO 数据链接链接失效反馈

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资源简介：

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

应用场景：

创建时间：

2024-01-31

酶结构解析

结核病药物靶点

M. tuberculosis 1-deoxy-d-xylulose-5-phosphate reductoisomerase bound to 1-deoxy-L-erythrulose Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 1-deoxy-L-erythrulose, MANGANESE (II) ION, .

Protein Data Bank Japan2023-09-20 更新70

M. tuberculosis DprE1 covalently bound to a nitrobenzoxacinone.

结核病药物靶点

蛋白酶-抑制剂复合物结构

M. tuberculosis DprE1 covalently bound to a nitrobenzoxacinone. Descriptor: 2-[(2~{S},6~{R})-2,6-dimethylpiperidin-1-yl]-8-nitro-6-(trifluoromethyl)-1,3-benzoxazin-4-one, Decaprenylphosphoryl-beta-D-r

Protein Data Bank Japan2024-11-13 更新40

Mycobacterium Tuberculosis Methionine aminopeptidase type 1c (C105N mutant).

结核病药物靶点

突变体研究

Mycobacterium Tuberculosis Methionine aminopeptidase type 1c (C105N mutant).

NIAID Data Ecosystem10

Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with SDDC-0001565 inhibitor

结核病药物靶点

蛋白质晶体

Crystal structure of dihydrofolate reductase from Mycobacterium ulcerans with SDDC-0001565 inhibitor Descriptor: 1,2-ETHANEDIOL, 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoi

Protein Data Bank Japan2023-10-11 更新50

Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice

结核病药物靶点

细菌代谢毒性机制

Trehalose biosynthesis is considered an attractive target for the development of antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium tuberculosis. The most common

Figshare2016-12-09 更新20

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

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