Nup153

ENCODES a protein that exhibits chromatin binding; double-stranded DNA binding; nuclear localization sequence binding; INVOLVED IN amyloid fibril formation (ortholog); negative regulation of RNA export from nucleus (ortholog); nuclear pore complex assembly (ortholog); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; ASSOCIATED WITH Pulmonary Atresia (ortholog); FOUND IN annulate lamellae; nuclear inclusion body; nuclear membrane; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene

编码一种表现出染色质结合、双链DNA结合、核定位序列结合的蛋白质；参与淀粉样纤维形成（同源）；对核RNA输出负调控（同源）；参与核孔复合物组装（同源）；参与mRNA核输出途径；RNA运输途径；与肺动脉闭锁（同源）相关；存在于环状层板、核包涵体、核膜中；与（+）川楝素B、2,3,7,8-四氯二苯并-对-二氧杂芑、2,4-二硝基甲苯相互作用。