Role of Myocardium-Derived Exosomal miRNAs in Doxorubicin-Induced Cardiomyopathy

Myocardium-derived exosomal miR-182 is upregulated in doxorubicin-induced cardiomyopathy and targets Taok2 in the MAPK pathway.心肌来源的外泌体miR-182在阿霉素诱导型心肌病中表达上调，并靶向丝裂原活化蛋白激酶（mitogen-activated protein kinase, MAPK）通路中的Taok2。