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RPS12 and UBC4 Are Related to Senescence Signal Production in the Ribosomal RNA Gene Cluster

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NIAID Data Ecosystem2026-03-14 收录
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We isolated yeast mutants that grew normally while Fob1 was overexpressed, expecting that some of the mutated genes would be related to the production of a senescence signal that elongates cell cycle, stops cell division and finally restricts replicative life span. The genomic DNA library from the mutants and wild-type cells were sequenced by Illumina Miseq. The filtered fastq data was analyzed by MUDI platform.

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2023-01-28
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